While many people use cannabidiol to ease pain, more scientific research is required to be certain it is safe. Understanding cannabidiol will help overcome the stigma associated with it.
Many people experience unwanted effects when taking cannabidiol (CBD) and there are other considerations before using CBD oil for pain.
In the following paragraphs, we examine how CBD oil works and how people may use it to ease chronic pain. Many plants contain cannabinoids, but people most commonly link them to cannabis. Unlike other cannabinoids – like tetrahydrocannabinol (THC) – CBD does not produce a euphoric “high” or psychoactive effect. This is because CBD will not change the same receptors as THC.
Your body comes with an endocannabinoid system (ECS) that receives and translates signals from cannabinoids. It generates some cannabinoids of the own, that are called endocannabinoids. The ECS really helps to regulate functions including sleep, immune-system responses, and pain.
When THC enters your body, it produces a “high” feeling by affecting the brain’s endocannabinoid receptors. This activates the brain’s reward system, producing pleasure chemicals such as dopamine.
Does CBD make you high?
CBD is definitely an entirely different compound from THC, as well as its effects are very complex. It is not psychoactive, meaning it will not create a “high” or change a person’s mind-set, however it influences the body to use their own endocannabinoids better.
According to one study posted to Neurotherapeutics, this is because CBD itself does very little to the ECS. Instead, it activates or inhibits other compounds in the endocannabinoid system.
For example, CBD stops against absorbing anandamide, a compound associated with regulating pain. So, increased levels of anandamide within the bloodstream may reduce the quantity of pain someone feels. Cannabidiol might also limit inflammation within the brain and central nervous system, which may benefit people experiencing pain, insomnia, and certain immune-system responses.
What exactly is CBD oil?
Different cannabis plants – also known as hemp or marijuana – contain different degrees of chemical compounds. How people breed the plant affects the CBD levels. Most CBD oil originates from industrial hemp, which often features a higher CBD content than marijuana. Makers of CBD oil use various methods to extract the compound. The extract is then put into a carrier oil and called CBD oil. CBD oil comes in many different strengths, and people utilize it in various ways. It is best to discuss CBD oil using a doctor before using it.
People have used CBD for thousands of years to treat various types of pain, but the medical community only have recently started to study it again. Here are among the possible benefits associated with CBD oil:
Arthritis pain – CBD oil is popular for easing pain associated with arthritis. A study in the European Journal of Pain used an animal model to find out if CBD might help people who have arthritis manage their pain. Researchers applied a topical gel containing CBD to rats with arthritis for 4 days. Their researchers note a significant drop in inflammation and warning signs of pain, without additional side effects. People using CBD oil for arthritis might find relief from their pain, but more human studies need to be completed to confirm these findings.
Multiple sclerosis – Multiple sclerosis (MS) is definitely an autoimmune ailment that affects the entire body through the nerves and brain. Muscle spasms are among the most common symptoms of MS. These spasms is really so great they cause constant pain in some people. One report found that short-term use of CBD oil could decrease the levels of spasticity an individual feels. The results are modest, but some people reported a reduction in symptoms. More studies on humans are needed to verify these results.
Chronic pain – The same report studied CBD use for general chronic pain. Researchers compiled the outcomes of multiple systematic reviews covering lots of trials and studies. Their research figured that there exists substantial evidence that cannabis is an excellent solution for chronic pain in adults. A different study inside the Journal of Experimental Medicine supports these results. This research suggests that using CBD is able to reduce pain and inflammation. They also found that subjects were not likely to develop a tolerance to the results of CBD, so they would not need to improve their dose continually. They noted that cannabinoids, including CBD, could offer helpful new treatments for those who have chronic pain.
CBD currently has an array of applications and promising possibilities. Such as:
* quitting smoking and drug withdrawal
* treating seizures and epilepsy
* anxiety treatment
* reducing some of the results of Alzheimer’s, as shown by initial research
* antipsychotic effects on people with schizophrenia
* future applications in combating acne, type 1 diabetes, and cancer
* Although more research must confirm some uses of CBD oil, it is actually shaping as a potentially promising and versatile treatment.
In June 2018, the U.S. Food and Drug Administration (FDA) approved one form of CBD being a treatment for people with two rare and particular forms of epilepsy, namely Lennox-Gastaut syndrome (LGS) or Dravet syndrome (DS). The company name of the drug is Epidiolex.
More generally, marijuana derived CBD products are not yet legal at the federal level however are legal under the laws of some states. Hemp derived CBD products that contain lower than .3% THC are legal federally but they are still illegal in yhvykk states. People must check their state’s laws and the ones of anywhere they plan to travel. They need to remember that the FDA tend not to approve or regulate nonprescription CBD products. Consequently, labeling may be inaccurate.